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What the FDA labels say about taking them together

Atropine and benazepril/hydrochlorothiazide

Benazepril/hydrochlorothiazide's FDA label of February 24, 2026 names atropine in its drug interactions section; the atropine labels PlainMeds reads (4) do not name benazepril/hydrochlorothiazide. The benazepril/hydrochlorothiazide label: “Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents, apparently due to a decrease in gastrointestinal motility and the stomach emptying …”

Check it at the source: the atropine FDA label on DailyMed (effective May 18, 2026, Hospira, Inc.); the benazepril/hydrochlorothiazide FDA label on DailyMed (effective February 24, 2026, Validus Pharmaceuticals LLC).

What does the atropine label say about benazepril/hydrochlorothiazide?

Atropine's label (effective May 18, 2026) and its 3 other brand-application labels do not name benazepril/hydrochlorothiazide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Atropine Sulfate), Hospira, Inc., effective May 18, 2026 (SPL set ad8916e7-206e-409e-2582-30d072845dd4), via openFDA; the full label on DailyMed

What does the benazepril/hydrochlorothiazide label say about atropine?

Benazepril/hydrochlorothiazide label, drug interactions

Drugs that alter gastrointestinal motility: The bioavailability of thiazide-type diuretics may be increased by anticholinergic agents (e.g., atropine, biperiden), apparently due to a decrease in gastrointestinal motility and the stomach emptying rate.

Source: FDA drug label (Lotensin HCT), Validus Pharmaceuticals LLC, effective February 24, 2026 (SPL set 94c4536f-e28e-48b1-8336-b3939917e99d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

22Atropine generic labelers
3Benazepril/hydrochlorothiazide generic labelers
AtropineBenazepril/hydrochlorothiazide
Labeled forn/aHigh blood pressure
Boxed warningNoYes
Pharmacy cost (NADAC)$7.74 per mL 1% eye drops$0.222 per tablet 20-12.5 mg tablet
Shortage nowIn shortageNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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