What the FDA labels say about taking them together
Atovaquone and ritonavir
Ritonavir's FDA label of July 23, 2026 names atovaquone in its drug interactions section; the atovaquone label PlainMeds reads does not name ritonavir. The ritonavir label: “Clinical significance is unknown; however, increase in atovaquone dose may be needed.”
Check it at the source: the atovaquone FDA label on DailyMed (effective March 20, 2026); the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).
What does the atovaquone label say about ritonavir?
Atovaquone's label (effective March 20, 2026) does not name ritonavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (MEPRON), GlaxoSmithKline LLC, effective March 20, 2026 (SPL set b426b6bf-f07e-4580-97ae-dfca1ddf5b8f), via openFDA; the full label on DailyMed
What does the ritonavir label say about atovaquone?
Ritonavir label, drug interactionsConcomitant Drug Class/Drug Name: Antiparasitic: atovaquone; Effect on Concentration of Ritonavir or Concomitant Drug: ↓ atovaquone; Clinical Comment: Clinical significance is unknown; however, increase in atovaquone dose may be needed.
Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Atovaquone | Ritonavir | |
|---|---|---|
| Labeled for | n/a | HIV |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.767 per mL 750 mg/5 mL suspension | $0.607 per tablet 100 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once