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What the FDA labels say about taking them together

Atorvastatin and eltrombopag

Eltrombopag's FDA label of December 18, 2025 names atorvastatin in its drug interactions section; the atorvastatin labels PlainMeds reads (2) do not name eltrombopag.

Check it at the source: the atorvastatin FDA label on DailyMed (effective April 15, 2024, Viatris Specialty LLC); the eltrombopag FDA label on DailyMed (effective December 18, 2025, Novartis Pharmaceuticals Corporation).

What does the atorvastatin label say about eltrombopag?

Atorvastatin's label (effective April 15, 2024) and its 1 other brand-application label do not name eltrombopag in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Lipitor), NDA020702 (Upjohn), as published by Viatris Specialty LLC, effective April 15, 2024 (SPL set a60cc18b-0631-4cf0-b021-9f52224ece65), via openFDA; the full label on DailyMed

What does the eltrombopag label say about atorvastatin?

Eltrombopag label, drug interactions

Use caution when concomitantly administering PROMACTA and drugs that are substrates of OATP1B1 (e.g., atorvastatin, bosentan, ezetimibe, fluvastatin, glyburide, olmesartan, pitavastatin, pravastatin, rosuvastatin, repaglinide, rifampin, simvastatin acid, SN-38 [active metabolite of irinotecan], valsartan) or breast cancer resistance protein (BCRP) (e.g., imatinib, irinotecan, lapatinib, methotrexate, mitoxantrone, rosuvastatin, sulfasalazine, topotecan).

Source: FDA drug label (Alvaiz, NDA216774), Teva Pharmaceuticals, Inc., effective January 1, 2026 (SPL set ed51e463-7a03-4858-bbd2-882ce4753d5a), via openFDA

Source: FDA drug label (PROMACTA), Novartis Pharmaceuticals Corporation, effective December 18, 2025 (SPL set 7714a0ed-34bb-46e6-a0a5-b363908b22c2), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

59Atorvastatin generic labelers
13Eltrombopag generic labelers
AtorvastatinEltrombopag
Labeled forHigh cholesterol, Angina, High triglycerides, Heart attack and coronary artery diseaseAnemia
Boxed warningNoYes
Pharmacy cost (NADAC)$0.0228 per tablet 10 mg tablet$25.85 per tablet 50 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?