Skip to main content

What the FDA labels say about taking them together

Atorvastatin and elbasvir/grazoprevir

Elbasvir/grazoprevir's FDA label of March 13, 2026 names atorvastatin in its drug interactions section; the atorvastatin labels PlainMeds reads (2) do not name elbasvir/grazoprevir. The elbasvir/grazoprevir label: “The dose of atorvastatin should not exceed a daily dose of 20 mg when co-administered with ZEPATIER.”

Check it at the source: the atorvastatin FDA label on DailyMed (effective April 15, 2024, Viatris Specialty LLC); the elbasvir/grazoprevir FDA label on DailyMed (effective March 13, 2026, Merck Sharp & Dohme LLC).

What does the atorvastatin label say about elbasvir/grazoprevir?

Atorvastatin's label (effective April 15, 2024) and its 1 other brand-application label do not name elbasvir/grazoprevir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Lipitor), NDA020702 (Upjohn), as published by Viatris Specialty LLC, effective April 15, 2024 (SPL set a60cc18b-0631-4cf0-b021-9f52224ece65), via openFDA; the full label on DailyMed

What does the elbasvir/grazoprevir label say about atorvastatin?

Elbasvir/grazoprevir label, drug interactions

Concomitant Drug Class/Drug Name: Atorvastatin; Effect on Concentration ↓ = decrease, ↑ = increase: ↑ atorvastatin; Clinical Comment: The dose of atorvastatin should not exceed a daily dose of 20 mg when co-administered with ZEPATIER.

Source: FDA drug label (ZEPATIER), Merck Sharp & Dohme LLC, effective March 13, 2026 (SPL set 164dc02a-9180-426a-b8b5-04ab39d2bbd4), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

59Atorvastatin generic labelers
0Elbasvir/grazoprevir generic labelers
AtorvastatinElbasvir/grazoprevir
Labeled forHigh cholesterol, Angina, High triglycerides, Heart attack and coronary artery diseaseHepatitis C
Boxed warningNoYes
Pharmacy cost (NADAC)$0.0228 per tablet 10 mg tabletn/a
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?