What the FDA labels say about taking them together
Atogepant and rifampin
Atogepant's FDA label of September 30, 2025 names rifampin in its drug interactions section; the rifampin label PlainMeds reads does not name atogepant. The atogepant label: “Coadministration of QULIPTA with steady-state rifampin, a strong CYP3A4 inducer and OATP1B1 and OATP1B3 inhibitor, resulted in a significant decrease in exposure of atogepant in healthy subjects.”
Check it at the source: the atogepant FDA label on DailyMed (effective September 30, 2025, AbbVie Inc.); the rifampin FDA label on DailyMed (effective February 11, 2026, Lupin Pharmaceuticals, Inc.).
What does the atogepant label say about rifampin?
Atogepant label, drug interactionsCoadministration of QULIPTA with steady-state rifampin, a strong CYP3A4 inducer and OATP1B1 and OATP1B3 inhibitor, resulted in a significant decrease in exposure of atogepant in healthy subjects [see Clinical Pharmacology ( 12.3 )].
Source: FDA drug label (Qulipta), AbbVie Inc., effective September 30, 2025 (SPL set 8c8ab8f4-32bd-497a-befa-70c8a51d8d52), via openFDA; the full label on DailyMed
What does the rifampin label say about atogepant?
Rifampin's label (effective February 11, 2026) does not name atogepant in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (rifampin), Lupin Pharmaceuticals, Inc., effective February 11, 2026 (SPL set b56004f0-f23d-47f6-80c7-39884fccbccc), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Atogepant | Rifampin | |
|---|---|---|
| Labeled for | Migraine | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $38.36 per tablet 10 mg tablet | $0.679 per capsule 300 mg capsule |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once