What the FDA labels say about taking them together
Atogepant and itraconazole
Atogepant's FDA label of September 30, 2025 names itraconazole in its drug interactions section; the itraconazole labels PlainMeds reads (2) do not name atogepant. The atogepant label: “Coadministration of QULIPTA with itraconazole, a strong CYP3A4 inhibitor, resulted in a significant increase in exposure of atogepant in healthy subjects.”
Check it at the source: the atogepant FDA label on DailyMed (effective September 30, 2025, AbbVie Inc.); the itraconazole FDA label on DailyMed (effective July 13, 2026, Janssen Pharmaceuticals, Inc.).
What does the atogepant label say about itraconazole?
Atogepant label, drug interactionsCoadministration of QULIPTA with itraconazole, a strong CYP3A4 inhibitor, resulted in a significant increase in exposure of atogepant in healthy subjects [see Clinical Pharmacology ( 12.3 )].
Source: FDA drug label (Qulipta), AbbVie Inc., effective September 30, 2025 (SPL set 8c8ab8f4-32bd-497a-befa-70c8a51d8d52), via openFDA; the full label on DailyMed
What does the itraconazole label say about atogepant?
Itraconazole's label (effective July 13, 2026) and its 1 other brand-application label do not name atogepant in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (SPORANOX), Janssen Pharmaceuticals, Inc., effective July 13, 2026 (SPL set a4d555fa-787c-40fb-bb7d-b0d4f7318fd0), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Atogepant | Itraconazole | |
|---|---|---|
| Labeled for | Migraine | Fungal infections |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $38.36 per tablet 10 mg tablet | $0.910 per capsule 100 mg capsule |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once