What the FDA labels say about taking them together
Atazanavir and salmeterol
Salmeterol's FDA label of October 10, 2022 names atazanavir in its drug interactions section; the atazanavir labels PlainMeds reads (2) do not name salmeterol. The salmeterol label: “The use of strong CYP3A4 inhibitors with SEREVENT DISKUS is not recommended because increased cardiovascular adverse effects may occur.”
Check it at the source: the atazanavir FDA label on DailyMed (effective August 6, 2025, Aurobindo Pharma Limited); the salmeterol FDA label on DailyMed (effective October 10, 2022, GlaxoSmithKline LLC).
What does the atazanavir label say about salmeterol?
Atazanavir's label (effective August 6, 2025) and its 1 other brand-application label do not name salmeterol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Atazanavir Sulfate), Aurobindo Pharma Limited, effective August 6, 2025 (SPL set 7fbea274-d6b5-4faa-bbf0-05fefab42114), via openFDA; the full label on DailyMed
What does the salmeterol label say about atazanavir?
Salmeterol label, drug interactionsThe use of strong CYP3A4 inhibitors (e.g., ritonavir, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, saquinavir, ketoconazole, telithromycin) with SEREVENT DISKUS is not recommended because increased cardiovascular adverse effects may occur.
Salmeterol label, warnings and precautionsInteractions with Strong Cytochrome P450 3A4 Inhibitors The use of strong cytochrome P450 3A4 (CYP3A4) inhibitors (e.g., ritonavir, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, saquinavir, ketoconazole, telithromycin) with SEREVENT DISKUS is not recommended because increased cardiovascular adverse effects may occur [see Drug Interactions ( 7.1 ), Clinical Pharmacology ( 12.3 )].
Source: FDA drug label (SEREVENT DISKUS), GlaxoSmithKline LLC, effective October 10, 2022 (SPL set 12d9728e-6b5c-4aee-bfb0-745e542ed2e4), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Atazanavir | Salmeterol | |
|---|---|---|
| Labeled for | HIV | Asthma, COPD |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $2.23 per capsule 300 mg capsule | $6.74 per unit 50 mcg |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once