What the FDA labels say about taking them together
Atazanavir and posaconazole
Posaconazole's FDA label of August 3, 2026 names atazanavir in its drug interactions section; the atazanavir labels PlainMeds reads (2) do not name posaconazole. The posaconazole label: “Mechanism and Clinical Effect (s); Ritonavir and atazanavir are CYP3A4 substrates and posaconazole increased plasma concentrations of these drugs.”
Check it at the source: the atazanavir FDA label on DailyMed (effective August 6, 2025, Aurobindo Pharma Limited); the posaconazole FDA label on DailyMed (effective August 3, 2026, Aurobindo Pharma Limited).
What does the atazanavir label say about posaconazole?
Atazanavir's label (effective August 6, 2025) and its 1 other brand-application label do not name posaconazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Atazanavir Sulfate), Aurobindo Pharma Limited, effective August 6, 2025 (SPL set 7fbea274-d6b5-4faa-bbf0-05fefab42114), via openFDA; the full label on DailyMed
What does the posaconazole label say about atazanavir?
Posaconazole label, drug interactionsMechanism and Clinical Effect (s); Ritonavir and atazanavir are CYP3A4 substrates and posaconazole increased plasma concentrations of these drugs [see ].
Source: FDA drug label (POSACONAZOLE), Aurobindo Pharma Limited, effective August 3, 2026 (SPL set f8a26673-261c-4e8e-b1e1-9e23aaf7f285), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Atazanavir | Posaconazole | |
|---|---|---|
| Labeled for | HIV | Fungal infections |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $2.23 per capsule 300 mg capsule | $2.03 per tablet 100 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once