What the FDA labels say about taking them together
Atazanavir and pimozide
Atazanavir's FDA label of August 6, 2025 names pimozide in its contraindications section; the pimozide label PlainMeds reads does not name atazanavir. The atazanavir label: “Coadministration of REYATAZ with pimozide is contraindicated. This is due to the potential for serious and/or life-threatening reactions such as cardiac arrhythmias.”
Check it at the source: the atazanavir FDA label on DailyMed (effective August 6, 2025, Aurobindo Pharma Limited); the pimozide FDA label on DailyMed (effective August 12, 2026, Par Health USA, LLC).
What does the atazanavir label say about pimozide?
Atazanavir label, contraindicationsDrug Class: Antipsychotics; Drugs within class that are contraindicated with atazanavir capsules: Lurasidone (with ritonavir), pimozide
Atazanavir label, drug interactionsConcomitant Drug Class/Specific Drugs: Antipsychotics: pimozide; Effect on Concentration of Atazanavir or Concomitant Drug: ↑ pimozide; Clinical Comment: Coadministration of atazanavir with pimozide is contraindicated. This is due to the potential for serious and/or life-threatening reactions such as cardiac arrhythmias [see ].
Source: FDA drug label (Reyataz, NDA021567), E.R. Squibb & Sons, L.L.C., effective December 5, 2024 (SPL set 165cff62-b284-4a27-a65d-9ec8a5bfcdd8), via openFDA
Source: FDA drug label (Atazanavir Sulfate), Aurobindo Pharma Limited, effective August 6, 2025 (SPL set 7fbea274-d6b5-4faa-bbf0-05fefab42114), via openFDA; the full label on DailyMed
What does the pimozide label say about atazanavir?
Pimozide's label (effective August 12, 2026) does not name atazanavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Pimozide), Par Health USA, LLC, effective August 12, 2026 (SPL set 70b079e2-a1f7-4a93-8685-d60a4d7c1280), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Atazanavir | Pimozide | |
|---|---|---|
| Labeled for | HIV | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $2.23 per capsule 300 mg capsule | $1.23 per tablet 1 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once