What the FDA labels say about taking them together
Atazanavir and lovastatin
Atazanavir's FDA label of August 6, 2025 names lovastatin in its contraindications section; the lovastatin label PlainMeds reads does not name atazanavir. The atazanavir label: “Coadministration of REYATAZ with lovastatin or simvastatin is contraindicated. This is due to the potential for serious reactions such as myopathy, including rhabdomyolysis.”
Check it at the source: the atazanavir FDA label on DailyMed (effective August 6, 2025, Aurobindo Pharma Limited); the lovastatin FDA label on DailyMed (effective May 6, 2026, Lupin Pharmaceuticals, Inc.).
What does the atazanavir label say about lovastatin?
Atazanavir label, contraindicationsDrug Class: Lipid-Modifying Agents:; Drugs within class that are contraindicated with atazanavir capsules: Lomitapide, lovastatin, simvastatin
Atazanavir label, drug interactionsConcomitant Drug Class/Specific Drugs: Lipid-modifying agents HMG-CoA reductase inhibitors: lovastatin, simvastatin; Effect on Concentration of Atazanavir or Concomitant Drug: ↑ lovastatin ↑ simvastatin; Clinical Comment: Coadministration of atazanavir with lovastatin or simvastatin is contraindicated. This is due to the potential for serious reactions such as myopathy, including rhabdomyolysis [see ].
Source: FDA drug label (Reyataz, NDA021567), E.R. Squibb & Sons, L.L.C., effective December 5, 2024 (SPL set 165cff62-b284-4a27-a65d-9ec8a5bfcdd8), via openFDA
Source: FDA drug label (Atazanavir Sulfate), Aurobindo Pharma Limited, effective August 6, 2025 (SPL set 7fbea274-d6b5-4faa-bbf0-05fefab42114), via openFDA; the full label on DailyMed
What does the lovastatin label say about atazanavir?
Lovastatin's label (effective May 6, 2026) does not name atazanavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lovastatin), Lupin Pharmaceuticals, Inc., effective May 6, 2026 (SPL set df7ddf4f-d569-431e-81f1-9129d7043150), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Atazanavir | Lovastatin | |
|---|---|---|
| Labeled for | HIV | High cholesterol, Heart attack and coronary artery disease |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $2.23 per capsule 300 mg capsule | $0.0436 per tablet 20 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once