Skip to main content

What the FDA labels say about taking them together

Atazanavir and eluxadoline

Eluxadoline's FDA label of July 16, 2024 names atazanavir in its drug interactions section; the atazanavir labels PlainMeds reads (2) do not name eluxadoline. The eluxadoline label: “Increased exposure to eluxadoline when coadministered with cyclosporine [ see Clinical Pharmacology () ]”

Check it at the source: the atazanavir FDA label on DailyMed (effective August 6, 2025, Aurobindo Pharma Limited); the eluxadoline FDA label on DailyMed (effective July 16, 2024, Allergan, Inc.).

What does the atazanavir label say about eluxadoline?

Atazanavir's label (effective August 6, 2025) and its 1 other brand-application label do not name eluxadoline in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Atazanavir Sulfate), Aurobindo Pharma Limited, effective August 6, 2025 (SPL set 7fbea274-d6b5-4faa-bbf0-05fefab42114), via openFDA; the full label on DailyMed

What does the eluxadoline label say about atazanavir?

Eluxadoline label, drug interactions

OATP1B1 Inhibitors Clinical Impact: Increased exposure to eluxadoline when coadministered with cyclosporine [ see Clinical Pharmacology () ] … eluxadoline-related adverse reactions [see Adverse Reactions ()]. Examples: cyclosporine, gemfibrozil, antiretrovirals (atazanavir, lopinavir, ritonavir, saquinavir, tipranavir), rifampin, eltrombopag

Source: FDA drug label (Viberzi), NDA206940 (Abbvie), as published by Allergan, Inc., effective July 16, 2024 (SPL set 7821bd40-4c84-4984-951b-6436ae20421a), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

4Atazanavir generic labelers
0Eluxadoline generic labelers
AtazanavirEluxadoline
Labeled forHIVIrritable bowel syndrome, Diarrhea
Boxed warningNoNo
Pharmacy cost (NADAC)$2.23 per capsule 300 mg capsule$28.09 per tablet 100 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?