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What the FDA labels say about taking them together

Aspirin/dipyridamole and salicylic acid

Aspirin/dipyridamole's FDA label of January 5, 2026 names salicylic acid in its drug interactions section; the salicylic acid label PlainMeds reads does not name aspirin/dipyridamole. The aspirin/dipyridamole label: “Anticonvulsants Salicylic acid can displace protein-bound phenytoin and valproic acid, leading to a decrease in the total concentration of phenytoin and an increase in serum valproic acid levels.”

Check it at the source: the aspirin/dipyridamole FDA label on DailyMed (effective January 5, 2026, Glenmark Pharmaceuticals Inc., USA); the salicylic acid FDA label on DailyMed (effective October 22, 2024).

What does the aspirin/dipyridamole label say about salicylic acid?

Aspirin/dipyridamole label, drug interactions

Anticonvulsants Salicylic acid can displace protein-bound phenytoin and valproic acid, leading to a decrease in the total concentration of phenytoin and an increase in serum valproic acid levels.

Source: FDA drug label (ASPRIN AND EXTENDED-RELEASE DIPYRIDAMOLE), Glenmark Pharmaceuticals Inc., USA, effective January 5, 2026 (SPL set 467d6ce3-bc05-4aa1-87cc-3214fd628d39), via openFDA; the full label on DailyMed

What does the salicylic acid label say about aspirin/dipyridamole?

Salicylic acid's label (effective October 22, 2024) does not name aspirin/dipyridamole in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (bareMinerals Blemish Rescue Skin-Clearing Loose Foundation Fair 1C), Orveon Global US LLC, effective October 22, 2024 (SPL set 139e2d26-76de-4ad3-a6e6-7465bf5987ad), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

9Aspirin/dipyridamole generic labelers
0Salicylic acid generic labelers
Aspirin/dipyridamoleSalicylic acid
Labeled forStroke preventionAcne, Pain, Psoriasis
Boxed warningNoNo
Pharmacy cost (NADAC)$0.559 per unit 25-200 mg$0.102 per patch Callus removers patch
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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