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What the FDA labels say about taking them together

Ascorbic acid, polyethylene glycol 3350 and 4 other ingredients and bisacodyl

Ascorbic acid, polyethylene glycol 3350 and 4 other ingredients's FDA label of October 31, 2025 names bisacodyl in its drug interactions section; the bisacodyl label PlainMeds reads does not name ascorbic acid, polyethylene glycol 3350 and 4 other ingredients. The ascorbic acid, polyethylene glycol 3350 and 4 other ingredients label: “Avoid use of stimulant laxatives while taking PLENVU.”

Check it at the source: the ascorbic acid, polyethylene glycol 3350 and 4 other ingredients FDA label on DailyMed (effective October 31, 2025, Salix Pharmaceuticals, Inc.); the bisacodyl FDA label on DailyMed (effective April 8, 2025).

What does the ascorbic acid, polyethylene glycol 3350 and 4 other ingredients label say about bisacodyl?

Ascorbic acid, polyethylene glycol 3350 and 4 other ingredients label, drug interactions

Avoid use of stimulant laxatives (e.g., bisacodyl, sodium picosulfate) while taking MoviPrep [see Warnings and Precautions ( 5.5 , 5.6 )].

Source: FDA drug label (Plenvu, NDA209381), Salix Pharmaceuticals, Inc, effective September 1, 2023 (SPL set 79f930fa-5674-4f30-8ae8-9448d6243797), via openFDA

Source: FDA drug label (MoviPrep), Salix Pharmaceuticals, Inc., effective October 31, 2025 (SPL set 8ff46193-2a3b-4de0-9572-775dda8cd8b2), via openFDA; the full label on DailyMed

What does the bisacodyl label say about ascorbic acid, polyethylene glycol 3350 and 4 other ingredients?

Bisacodyl's label (effective April 8, 2025) does not name ascorbic acid, polyethylene glycol 3350 and 4 other ingredients in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Dulcolax Stimulant Laxative), Chattem, Inc., effective April 8, 2025 (SPL set f1e4b28a-ed74-4eff-bd10-b2bfaf7483b0), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Ascorbic acid, polyethylene glycol 3350 and 4 other ingredients generic labelers
0Bisacodyl generic labelers
Ascorbic acid, polyethylene glycol 3350 and 4 other ingredientsBisacodyl
Labeled forn/aConstipation
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$0.320 per suppository 10 mg suppository
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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