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What the FDA labels say about taking them together

Ascorbic acid, peg 3350 and 4 other ingredients and bisacodyl

Ascorbic acid, peg 3350 and 4 other ingredients's FDA label of April 14, 2022 names bisacodyl in its drug interactions section; the bisacodyl label PlainMeds reads does not name ascorbic acid, peg 3350 and 4 other ingredients. The ascorbic acid, peg 3350 and 4 other ingredients label: “Avoid use of stimulant laxatives while taking PEG-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate, and Ascorbic Acid for Oral Solution.”

Check it at the source: the ascorbic acid, peg 3350 and 4 other ingredients FDA label on DailyMed (effective April 14, 2022, Teva Pharmaceuticals USA, Inc.); the bisacodyl FDA label on DailyMed (effective April 8, 2025).

What does the ascorbic acid, peg 3350 and 4 other ingredients label say about bisacodyl?

Ascorbic acid, peg 3350 and 4 other ingredients label, drug interactions

Avoid use of stimulant laxatives (e.g., bisacodyl, sodium picosulfate) while taking PEG-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate, and Ascorbic Acid for Oral Solution [see Warnings and Precautions ( 5.5 , 5.6 )].

Source: FDA drug label (PEG-3350, SODIUM SULFATE, SODIUM CHLORIDE, POTASSIUM CHLORIDE, SODIUM ASCORBATE AND ASCORBIC ACID), ANDA090145 (Novel Labs Inc), as published by Teva Pharmaceuticals USA, Inc., effective April 14, 2022 (SPL set 475a06c6-f295-406c-a110-f1497cf51566), via openFDA; the full label on DailyMed

What does the bisacodyl label say about ascorbic acid, peg 3350 and 4 other ingredients?

Bisacodyl's label (effective April 8, 2025) does not name ascorbic acid, peg 3350 and 4 other ingredients in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Dulcolax Stimulant Laxative), Chattem, Inc., effective April 8, 2025 (SPL set f1e4b28a-ed74-4eff-bd10-b2bfaf7483b0), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

1Ascorbic acid, peg 3350 and 4 other ingredients generic labelers
0Bisacodyl generic labelers
Ascorbic acid, peg 3350 and 4 other ingredientsBisacodyl
Labeled forn/aConstipation
Boxed warningNoNo
Pharmacy cost (NADAC)$79.53 per unit 3350-sod sul-nacl-kcl-ascb-c 100-7.5-2.691-1.015-5.9-4.7g$0.320 per suppository 10 mg suppository
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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