What the FDA labels say about taking them together
Artemether/lumefantrine and etravirine
Etravirine's FDA label of August 15, 2023 names artemether/lumefantrine in its drug interactions section; the artemether/lumefantrine label PlainMeds reads does not name etravirine. The etravirine label: “Antimalarial: artemether/lumefantrine ↔ etravirine ↓ artemether ↓ dihydroartemisinin ↓ lumefantrine Caution is warranted when co-administering INTELENCE and artemether/lumefantrine as it is unknown whether the decrease …”
Check it at the source: the artemether/lumefantrine FDA label on DailyMed (effective March 26, 2026, Novartis Pharmaceuticals Corporation); the etravirine FDA label on DailyMed (effective August 15, 2023, Janssen Products LP).
What does the artemether/lumefantrine label say about etravirine?
Artemether/lumefantrine's label (effective March 26, 2026) does not name etravirine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (COARTEM), Novartis Pharmaceuticals Corporation, effective March 26, 2026 (SPL set 7866ec19-dfac-47d4-a53f-511a12643cbf), via openFDA; the full label on DailyMed
What does the etravirine label say about artemether/lumefantrine?
Etravirine label, drug interactionsAntimalarial: artemether/lumefantrine ↔ etravirine ↓ artemether ↓ dihydroartemisinin ↓ lumefantrine Caution is warranted when co-administering INTELENCE and artemether/lumefantrine as it is unknown whether the decrease in exposure of artemether or its active metabolite, dihydroartemisinin, could result in decreased antimalarial efficacy.
Source: FDA drug label (Intelence), Janssen Products LP, effective August 15, 2023 (SPL set 6a9cbc29-9f15-4b24-8d86-206b82887f3d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Artemether/lumefantrine | Etravirine | |
|---|---|---|
| Labeled for | n/a | HIV |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $5.36 per tablet Coartem tablets | $9.94 per tablet 200 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once