What the FDA labels say about taking them together
Artemether/lumefantrine and cobicistat/darunavir
Cobicistat/darunavir's FDA label of February 1, 2026 names artemether/lumefantrine in its drug interactions section; the artemether/lumefantrine label PlainMeds reads does not name cobicistat/darunavir. The cobicistat/darunavir label: “Antimalarial: artemether/lumefantrine artemether: effect unknown lumefantrine: effect unknown Monitor for a potential decrease of antimalarial efficacy or potential QT prolongation.”
Check it at the source: the artemether/lumefantrine FDA label on DailyMed (effective March 26, 2026, Novartis Pharmaceuticals Corporation); the cobicistat/darunavir FDA label on DailyMed (effective February 1, 2026, Janssen Products, LP).
What does the artemether/lumefantrine label say about cobicistat/darunavir?
Artemether/lumefantrine's label (effective March 26, 2026) does not name cobicistat/darunavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (COARTEM), Novartis Pharmaceuticals Corporation, effective March 26, 2026 (SPL set 7866ec19-dfac-47d4-a53f-511a12643cbf), via openFDA; the full label on DailyMed
What does the cobicistat/darunavir label say about artemether/lumefantrine?
Cobicistat/darunavir label, drug interactionsAntimalarial: artemether/lumefantrine artemether: effect unknown lumefantrine: effect unknown Monitor for a potential decrease of antimalarial efficacy or potential QT prolongation.
Source: FDA drug label (PREZCOBIX), Janssen Products, LP, effective February 1, 2026 (SPL set 9c38fdb6-d0ba-4f16-a0e3-85d9ec334d9f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Artemether/lumefantrine | Cobicistat/darunavir | |
|---|---|---|
| Labeled for | n/a | HIV |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $5.36 per tablet Coartem tablets | $79.99 per tablet 800 mg-150 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once