What the FDA labels say about taking them together
Aripiprazole and valproic acid
Neither FDA label names the other in its interaction, contraindication or warning sections. A label lists the interactions its studies and reports found; it is not a complete list, so ask a pharmacist before combining medicines. Labels read October 8, 2026.
Check it at the source: the aripiprazole FDA label on DailyMed (effective January 29, 2025, Otsuka America Pharmaceutical, Inc.); the valproic acid FDA label on DailyMed (effective January 24, 2025, PAI Holdings, LLC dba PAI Pharma).
What does the aripiprazole label say about valproic acid?
Aripiprazole's label (effective January 29, 2025) and its 3 other brand-application labels do not name valproic acid in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ABILIFY), Otsuka America Pharmaceutical, Inc., effective January 29, 2025 (SPL set c040bd1d-45b7-49f2-93ea-aed7220b30ac), via openFDA; the full label on DailyMed
What does the valproic acid label say about aripiprazole?
Valproic acid's label (effective January 24, 2025) does not name aripiprazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (VALPROIC ACID), PAI Holdings, LLC dba PAI Pharma, effective January 24, 2025 (SPL set 7d5cb52e-37dd-4dfa-a6f4-09f9548846c6), via openFDA; the full label on DailyMed
A pharmacist or prescriber can say whether these two medicines suit one person together; PlainMeds does not grade interactions.
Both medicines on the record
| Aripiprazole | Valproic acid | |
|---|---|---|
| Labeled for | Depression, Bipolar disorder, Schizophrenia | Seizures and epilepsy, Migraine |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.110 per tablet 5 mg tablet | $0.243 per capsule 250 mg capsule |
| Shortage now | No current entry | Listed; available |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once