What the FDA labels say about taking them together
Aripiprazole and milsaperidone
Milsaperidone's FDA label of February 27, 2026 names aripiprazole in its warnings and precautions section; the aripiprazole labels PlainMeds reads (4) do not name milsaperidone.
Check it at the source: the aripiprazole FDA label on DailyMed (effective January 29, 2025, Otsuka America Pharmaceutical, Inc.); the milsaperidone FDA label on DailyMed (effective February 27, 2026, Vanda Pharmaceuticals Inc.).
What does the aripiprazole label say about milsaperidone?
Aripiprazole's label (effective January 29, 2025) and its 3 other brand-application labels do not name milsaperidone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ABILIFY), Otsuka America Pharmaceutical, Inc., effective January 29, 2025 (SPL set c040bd1d-45b7-49f2-93ea-aed7220b30ac), via openFDA; the full label on DailyMed
What does the milsaperidone label say about aripiprazole?
Milsaperidone label, warnings and precautionsPatients with Dementia-Related Psychosis In placebo-controlled trials in elderly patients with dementia-related psychosis treated with risperidone, aripiprazole, or olanzapine had a higher incidence of stroke and transient ischemic attack, including fatal stroke compared to those treated with placebo.
Source: FDA drug label (BYSANTI), Vanda Pharmaceuticals Inc., effective February 27, 2026 (SPL set 254a1c01-4a4c-4bdd-85d6-1f23f2e4e6f8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Aripiprazole | Milsaperidone | |
|---|---|---|
| Labeled for | Depression, Bipolar disorder, Schizophrenia | Schizophrenia, Bipolar disorder |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.110 per tablet 5 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once