What the FDA labels say about taking them together
Arginine and cefepime
Cefepime's FDA label (Cefepime Hydrochloride And Dextrose) of April 7, 2026 names arginine in its warnings and precautions section; the arginine label PlainMeds reads does not name cefepime. The cefepime label: “Arginine has been shown to alter glucose metabolism and elevate serum potassium transiently when administered at 33 times the amount provided by the maximum recommended human dose of cefepime.”
Check it at the source: the arginine FDA label on DailyMed (effective April 2, 2024, Pharmacia & Upjohn Company LLC); the cefepime FDA label on DailyMed (effective November 15, 2021, Qilu Pharmaceutical Co., Ltd.).
What does the arginine label say about cefepime?
Arginine's label (effective April 2, 2024) does not name cefepime in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (R-Gene), Pharmacia & Upjohn Company LLC, effective April 2, 2024 (SPL set 6accf33f-9841-4327-8923-93c42020ef12), via openFDA; the full label on DailyMed
What does the cefepime label say about arginine?
Cefepime Hydrochloride And Dextrose label (B. Braun Medical Inc., April 7, 2026), warnings and precautionsArginine has been shown to alter glucose metabolism and elevate serum potassium transiently when administered at 33 times the amount provided by the maximum recommended human dose of cefepime.
Source: FDA drug label (Cefepime Hydrochloride And Dextrose, NDA050821), B. Braun Medical Inc., effective April 7, 2026 (SPL set 57517a0e-ec1b-4605-a7cc-7e3801158ec9), via openFDA
Source: FDA drug label (Cefepime), Qilu Pharmaceutical Co., Ltd., effective November 15, 2021 (SPL set 80b4c811-4a71-47fb-8565-85ce9d0f782c), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Arginine | Cefepime | |
|---|---|---|
| Labeled for | n/a | Urinary tract infections |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once