What the FDA labels say about taking them together
Arformoterol and salmeterol
Arformoterol's FDA label of April 14, 2026 names salmeterol in its warnings and precautions section, and salmeterol's label names arformoterol too. The arformoterol label: “A 28-week, placebo-controlled US study comparing the safety of another LABA (salmeterol) with placebo, each added to usual asthma therapy, showed an increase in asthma-related deaths in patients receiving salmeterol …”
Check it at the source: the arformoterol FDA label on DailyMed (effective April 14, 2026, Sun Pharmaceutical Industries, Inc.); the salmeterol FDA label on DailyMed (effective October 10, 2022, GlaxoSmithKline LLC).
What does the arformoterol label say about salmeterol?
Arformoterol label, warnings and precautionsA 28-week, placebo-controlled US study comparing the safety of another LABA (salmeterol) with placebo, each added to usual asthma therapy, showed an increase in asthma-related deaths in patients receiving salmeterol (13/13,176 in patients treated with salmeterol vs. 3/13,179 in patients treated with placebo;
Source: FDA drug label (Arformoterol Tartrate), Sun Pharmaceutical Industries, Inc., effective April 14, 2026 (SPL set f1005878-0c48-4b9a-843e-b6cf6b8bb251), via openFDA; the full label on DailyMed
What does the salmeterol label say about arformoterol?
Salmeterol label, warnings and precautionsPatients using SEREVENT DISKUS should not use another medicine containing a LABA (e.g., formoterol fumarate, arformoterol tartrate, indacaterol) for any reason.
Source: FDA drug label (SEREVENT DISKUS), GlaxoSmithKline LLC, effective October 10, 2022 (SPL set 12d9728e-6b5c-4aee-bfb0-745e542ed2e4), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Arformoterol | Salmeterol | |
|---|---|---|
| Labeled for | COPD | Asthma, COPD |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.633 per mL 15 mcg/2 mL solution | $6.74 per unit 50 mcg |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once