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What the FDA labels say about taking them together

Apomorphine and haloperidol

Apomorphine's FDA label of February 24, 2022 names haloperidol in its warnings and precautions section; the haloperidol labels PlainMeds reads (2) do not name apomorphine.

Check it at the source: the apomorphine FDA label on DailyMed (effective February 24, 2022, TruPharma, LLC); the haloperidol FDA label on DailyMed (effective April 23, 2026, PD-Rx Pharmaceuticals, Inc.).

What does the apomorphine label say about haloperidol?

Apomorphine label, warnings and precautions

Antiemetics with anti-dopaminergic actions (e.g., haloperidol, chlorpromazine, promethazine, prochlorperazine, metaclopramide) have the potential to worsen the symptoms in patients with Parkinson's disease and should be avoided.

Onapgo label (MDD US Operations, LLC, a subsidiary of Supernus Pharmaceuticals, Inc, July 10, 2026), warnings and precautions

Antiemetics with anti-dopaminergic actions (e.g., haloperidol, chlorpromazine, promethazine, prochlorperazine, metoclopramide) have the potential to worsen the symptoms in patients with Parkinson's disease (PD) and therefore the benefits and risks of treatment with these antiemetics should be carefully considered.

Source: FDA drug label (Onapgo, NDA214056), MDD US Operations, LLC, a subsidiary of Supernus Pharmaceuticals, Inc, effective July 10, 2026 (SPL set f3552b6e-5ae7-4993-aa1a-e399c4a7080a), via openFDA

Source: FDA drug label (apomorphine hydrocloride), ANDA212025 (Tp Anda Holdings), as published by TruPharma, LLC, effective February 24, 2022 (SPL set aedf70e4-1949-44bc-bf1b-0f282c4f0705), via openFDA; the full label on DailyMed

What does the haloperidol label say about apomorphine?

Haloperidol's label (effective April 23, 2026) and its 1 other brand-application label do not name apomorphine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Haloperidol), PD-Rx Pharmaceuticals, Inc., effective April 23, 2026 (SPL set 533b0b4c-cbd6-4ec0-a333-8b04b5b43a1d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

1Apomorphine generic labelers
41Haloperidol generic labelers
ApomorphineHaloperidol
Labeled forParkinson's diseaseSchizophrenia
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$15.60 per mL 100 mg/mL vial
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?