What the FDA labels say about taking them together
Anti-inhibitor coagulant complex and emicizumab
Anti-inhibitor coagulant complex's FDA label of November 27, 2025 names emicizumab in its drug interactions section; the emicizumab label PlainMeds reads does not name anti-inhibitor coagulant complex. The anti-inhibitor coagulant complex label: “The safety and efficacy of FEIBA for breakthrough bleeding in patients receiving emicizumab has not been established.”
Check it at the source: the anti-inhibitor coagulant complex FDA label on DailyMed (effective November 27, 2025); the emicizumab FDA label on DailyMed (effective July 11, 2025, Genentech, Inc.).
What does the anti-inhibitor coagulant complex label say about emicizumab?
Anti-inhibitor coagulant complex label, drug interactionsClinical experience from an emicizumab clinical trial suggests that a potential drug interaction may exist with emicizumab when FEIBA was used as part of a treatment regimen for breakthrough bleeding 6 [see Warnings and Precautions (5.1) ].
Anti-inhibitor coagulant complex label, warnings and precautionsThe safety and efficacy of FEIBA for breakthrough bleeding in patients receiving emicizumab has not been established.
Source: FDA drug label (FEIBA), Takeda Pharmaceuticals America, Inc., effective November 27, 2025 (SPL set 752604e5-4ea2-44f4-83ed-1569373f6412), via openFDA; the full label on DailyMed
What does the emicizumab label say about anti-inhibitor coagulant complex?
Emicizumab's label (effective July 11, 2025) does not name anti-inhibitor coagulant complex in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Hemlibra), Genentech, Inc., effective July 11, 2025 (SPL set 2483adba-fab6-4d1b-96c5-c195577ed071), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Anti-inhibitor coagulant complex | Emicizumab | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once