What the FDA labels say about taking them together
Anagrelide and procainamide
Anagrelide's FDA label of April 8, 2026 names procainamide in its drug interactions section; the procainamide label PlainMeds reads does not name anagrelide. The anagrelide label: “Drugs that Prolong QT Avoid use of AGRYLIN in patients taking medications that may prolong QT interval.”
Check it at the source: the anagrelide FDA label on DailyMed (effective April 8, 2026, Takeda Pharmaceuticals America, Inc.); the procainamide FDA label on DailyMed (effective February 17, 2025, Caplin Steriles Limited).
What does the anagrelide label say about procainamide?
Anagrelide label, drug interactionsDrugs that Prolong QT Avoid use of AGRYLIN in patients taking medications that may prolong QT interval (including, but not limited to, chloroquine, clarithromycin, haloperidol, methadone, moxifloxacin, amiodarone, disopyramide, procainamide, and pimozide) [see Warnings and Precautions (5.1) and Clinical Pharmacology (12.2) ].
Source: FDA drug label (Agrylin), Takeda Pharmaceuticals America, Inc., effective April 8, 2026 (SPL set cb960074-99c1-4a73-941f-f0644a7ec219), via openFDA; the full label on DailyMed
What does the procainamide label say about anagrelide?
Procainamide's label (effective February 17, 2025) does not name anagrelide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Procainamide Hydrochloride), Caplin Steriles Limited, effective February 17, 2025 (SPL set fcaa5e9a-3c8a-4796-aa87-626268b6cf60), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Anagrelide | Procainamide | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.729 per capsule 0.5 mg capsule | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once