What the FDA labels say about taking them together
Anagrelide and omeprazole
Anagrelide's FDA label of April 8, 2026 names omeprazole in its drug interactions section; the omeprazole labels PlainMeds reads (2) do not name anagrelide. The anagrelide label: “Patients taking concomitant CYP1A2 inducers (e.g., omeprazole) may need to have their dose titrated to compensate for the decrease in AGRYLIN exposure.”
Check it at the source: the anagrelide FDA label on DailyMed (effective April 8, 2026, Takeda Pharmaceuticals America, Inc.); the omeprazole FDA label on DailyMed (effective April 22, 2024, Apotex Corp).
What does the anagrelide label say about omeprazole?
Anagrelide label, drug interactionsPatients taking concomitant CYP1A2 inducers (e.g., omeprazole) may need to have their dose titrated to compensate for the decrease in AGRYLIN exposure.
Source: FDA drug label (Agrylin), Takeda Pharmaceuticals America, Inc., effective April 8, 2026 (SPL set cb960074-99c1-4a73-941f-f0644a7ec219), via openFDA; the full label on DailyMed
What does the omeprazole label say about anagrelide?
Omeprazole's label (effective April 22, 2024) and its 1 other brand-application label do not name anagrelide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Omeprazole), Apotex Corp, effective April 22, 2024 (SPL set b83329ac-a65e-b3af-a3fb-c5a6c740e5e7), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Anagrelide | Omeprazole | |
|---|---|---|
| Labeled for | n/a | Acid reflux and ulcers |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.729 per capsule 0.5 mg capsule | $0.0295 per capsule 20 mg capsule |
| Shortage now | A presentation being discontinued | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once