What the FDA labels say about taking them together
Amphetamine and meperidine
Amphetamine's FDA label of August 20, 2026 names meperidine in its drug interactions section; the meperidine labels PlainMeds reads (2) do not name amphetamine.
Check it at the source: the amphetamine FDA label on DailyMed (effective August 20, 2026, Aurolife Pharma, LLC); the meperidine FDA label on DailyMed (effective November 29, 2025, EPIC PHARMA, LLC).
What does the amphetamine label say about meperidine?
Amphetamine label, drug interactionsMeperidine Amphetamines potentiate the analgesic effect of meperidine.
Source: FDA drug label (Amphetamine Sulfate), Aurolife Pharma, LLC, effective August 20, 2026 (SPL set 20735c2e-6304-425f-a4e4-584f6f90d6a0), via openFDA; the full label on DailyMed
What does the meperidine label say about amphetamine?
Meperidine's label (effective November 29, 2025) and its 1 other brand-application label do not name amphetamine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Meperidine Hydrochloride), EPIC PHARMA, LLC, effective November 29, 2025 (SPL set fae5cc34-5917-4445-9516-25f97ffca8db), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amphetamine | Meperidine | |
|---|---|---|
| Labeled for | ADHD | Pain |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.449 per tablet 10 mg tablet | $0.157 per mL 50 mg/5 mL solution |
| Shortage now | No current entry | Listed; available |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once