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What the FDA labels say about taking them together

Amoxapine and dronabinol

Dronabinol's FDA label of May 6, 2026 names amoxapine in its warnings and precautions section; the amoxapine label PlainMeds reads does not name dronabinol. The dronabinol label: “Avoid concomitant use of other drugs that are also associated with similar cardiac effects.”

Check it at the source: the amoxapine FDA label on DailyMed (effective December 18, 2024, Chartwell RX, LLC); the dronabinol FDA label on DailyMed (effective May 6, 2026, Ascend Laboratories, LLC).

What does the amoxapine label say about dronabinol?

Amoxapine's label (effective December 18, 2024) does not name dronabinol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Amoxapine), Chartwell RX, LLC, effective December 18, 2024 (SPL set eed5e856-dd7b-4eaa-9dad-508f2bef9328), via openFDA; the full label on DailyMed

What does the dronabinol label say about amoxapine?

Dronabinol label, warnings and precautions

Avoid concomitant use of other drugs that are also associated with similar cardiac effects (e.g., amphetamines, other sympathomimetic agents, atropine, amoxapine, scopolamine, antihistamines, other anticholinergic agents, amitriptyline, desipramine, other tricyclic antidepressants).

Source: FDA drug label (Dronabinol), NDA018651 (Alkem Labs Ltd), as published by Ascend Laboratories, LLC, effective May 6, 2026 (SPL set adb1801c-0fb5-4e16-b969-1db91230e0b9), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

2Amoxapine generic labelers
1Dronabinol generic labelers
AmoxapineDronabinol
Labeled forDepression, Anxietyn/a
Boxed warningYesNo
Pharmacy cost (NADAC)n/a$3.35 per capsule 5 mg capsule
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?