What the FDA labels say about taking them together
Amlodipine/telmisartan and nitroglycerin
Amlodipine/telmisartan's FDA label of January 30, 2023 names nitroglycerin in its drug interactions section; nitroglycerin's label does not name amlodipine/telmisartan itself but warns about its class (ARBs (angiotensin II receptor blockers), Calcium channel blockers, Calcium channel blockers (dihydropyridines)).
Check it at the source: the amlodipine/telmisartan FDA label on DailyMed (effective January 30, 2023, Alembic Pharmaceuticals Limited); the nitroglycerin FDA label on DailyMed (effective February 15, 2023, Viatris Specialty LLC).
What does the amlodipine/telmisartan label say about nitroglycerin?
Amlodipine/telmisartan label, drug interactionsInteractions with Amlodipine In clinical trials, amlodipine has been safely administered with thiazide diuretics, beta-blockers, angiotensin-converting enzyme inhibitors, long-acting nitrates, sublingual nitroglycerin, digoxin, warfarin, non-steroidal anti-inflammatory drugs, antibiotics, and oral hypoglycemic drugs.
Source: FDA drug label (Telmisartan and Amlodipine), Alembic Pharmaceuticals Limited, effective January 30, 2023 (SPL set 15b438b4-4874-43f4-a50a-4e6f3e5530ac), via openFDA; the full label on DailyMed
What does the nitroglycerin label say about amlodipine/telmisartan?
Nitroglycerin's label does not name amlodipine/telmisartan itself; it warns about its class (ARBs (angiotensin II receptor blockers), Calcium channel blockers, Calcium channel blockers (dihydropyridines)):
Nitroglycerin label, drug interactionsMarked symptomatic orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used in combination.
Nitroglycerin label, drug interactionsThe vasodilating effects of nitroglycerin may be additive with those of antihypertensives (e.g., beta-blockers, calcium channel blockers and tricyclic antidepressants) and may cause increased hypotensive effects..
Source: FDA drug label (Nitrostat), Viatris Specialty LLC, effective February 15, 2023 (SPL set 9a52da75-d0af-4237-96c0-0b12adfa8636), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amlodipine/telmisartan | Nitroglycerin | |
|---|---|---|
| Labeled for | High blood pressure | Angina, High blood pressure, Heart failure, Heart attack and coronary artery disease |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $2.88 per unit 40-10 | $0.127 per tablet 0.4 mg tablet sl |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once