What the FDA labels say about taking them together
Amlodipine/telmisartan and ketoconazole
Amlodipine/telmisartan's FDA label of January 30, 2023 names ketoconazole in its drug interactions section; the ketoconazole label PlainMeds reads does not name amlodipine/telmisartan. The amlodipine/telmisartan label: “However, strong inhibitors of CYP3A4 may increase the plasma concentrations of amlodipine to a greater extent.”
Check it at the source: the amlodipine/telmisartan FDA label on DailyMed (effective January 30, 2023, Alembic Pharmaceuticals Limited); the ketoconazole FDA label on DailyMed (effective January 28, 2026, E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC).
What does the amlodipine/telmisartan label say about ketoconazole?
Amlodipine/telmisartan label, drug interactionsHowever, strong inhibitors of CYP3A4 (e.g., ketoconazole, itraconazole, ritonavir) may increase the plasma concentrations of amlodipine to a greater extent.
Source: FDA drug label (Telmisartan and Amlodipine), Alembic Pharmaceuticals Limited, effective January 30, 2023 (SPL set 15b438b4-4874-43f4-a50a-4e6f3e5530ac), via openFDA; the full label on DailyMed
What does the ketoconazole label say about amlodipine/telmisartan?
Ketoconazole's label (effective January 28, 2026) does not name amlodipine/telmisartan in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ketoconazole), E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC, effective January 28, 2026 (SPL set cad7c647-34a9-4e4e-83b3-8d78e58f588f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amlodipine/telmisartan | Ketoconazole | |
|---|---|---|
| Labeled for | High blood pressure | Fungal infections |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $2.88 per unit 40-10 | $0.249 per gram 2% cream |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once