What the FDA labels say about taking them together
Amlodipine and levamlodipine
Levamlodipine's FDA label of December 11, 2024 names amlodipine in its contraindications section; the amlodipine labels PlainMeds reads (4) do not name levamlodipine. The levamlodipine label: “CONTRAINDICATIONS Levamlodipine is contraindicated in patients with known sensitivity to amlodipine.”
Check it at the source: the amlodipine FDA label on DailyMed (effective February 15, 2023, Viatris Specialty LLC); the levamlodipine FDA label on DailyMed (effective December 11, 2024, CSPC Ouyi Pharmaceutical Co. Ltd).
What does the amlodipine label say about levamlodipine?
Amlodipine's label (effective February 15, 2023) and its 3 other brand-application labels do not name levamlodipine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Norvasc), Viatris Specialty LLC, effective February 15, 2023 (SPL set 7367289c-b0b0-466a-83e2-558e2985c29f), via openFDA; the full label on DailyMed
What does the levamlodipine label say about amlodipine?
Levamlodipine label, contraindicationsCONTRAINDICATIONS Levamlodipine is contraindicated in patients with known sensitivity to amlodipine.
Levamlodipine label, drug interactionsDrugs on Amlodipine CYP3A Inhibitors Co-administration with CYP3A inhibitors (moderate and strong) results in increased systemic exposure to amlodipine and may require dose reduction.
Levamlodipine label, warnings and precautionsHowever, acute hypotension is unlikely. ( 5.1 ) Worsening angina and acute myocardial infarction can develop after starting or increasing the dose of amlodipine, particularly in patients with severe obstructive coronary artery disease. ( 5.2 ) Titrate slowly in patients with severe hepatic impairment.
Source: FDA drug label (Conjupri), CSPC Ouyi Pharmaceutical Co. Ltd, effective December 11, 2024 (SPL set c3cca66e-348a-43e8-8f96-e995104dae3d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amlodipine | Levamlodipine | |
|---|---|---|
| Labeled for | High blood pressure, Angina, Heart attack and coronary artery disease | High blood pressure |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0102 per tablet 5 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once