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What the FDA labels say about taking them together

Amlodipine and fosamprenavir

Fosamprenavir's FDA label of September 15, 2023 names amlodipine in its drug interactions section; the amlodipine labels PlainMeds reads (4) do not name fosamprenavir. The fosamprenavir label: “Use with caution. Clinical monitoring of patients is recommended.”

Check it at the source: the amlodipine FDA label on DailyMed (effective February 15, 2023, Viatris Specialty LLC); the fosamprenavir FDA label on DailyMed (effective September 15, 2023, Mylan Pharmaceuticals Inc.).

What does the amlodipine label say about fosamprenavir?

Amlodipine's label (effective February 15, 2023) and its 3 other brand-application labels do not name fosamprenavir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Norvasc), Viatris Specialty LLC, effective February 15, 2023 (SPL set 7367289c-b0b0-466a-83e2-558e2985c29f), via openFDA; the full label on DailyMed

What does the fosamprenavir label say about amlodipine?

Fosamprenavir label, drug interactions

Concomitant Drug Class/Drug Name: Calcium channel blockers: Diltiazem, felodipine, nifedipine, nicardipine, nimodipine, verapamil, amlodipine, nisoldipine, isradipine; Effect on Concentration of Amprenavir or Concomitant Drug: ↑ Calcium channel blockers; Clinical Comment: Use with caution. Clinical monitoring of patients is recommended.

Source: FDA drug label (Fosamprenavir Calcium), Mylan Pharmaceuticals Inc., effective September 15, 2023 (SPL set 3a1424d8-844c-4e24-9ebd-b2c2b61b61a3), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

42Amlodipine generic labelers
2Fosamprenavir generic labelers
AmlodipineFosamprenavir
Labeled forHigh blood pressure, Angina, Heart attack and coronary artery diseaseHIV
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0102 per tablet 5 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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