What the FDA labels say about taking them together
Amlodipine and erythromycin
Amlodipine's FDA label of February 15, 2023 names erythromycin in its drug interactions section, and erythromycin's label names amlodipine too. The amlodipine label: “Erythromycin co-administration in healthy volunteers did not significantly change amlodipine systemic exposure.”
Check it at the source: the amlodipine FDA label on DailyMed (effective February 15, 2023, Viatris Specialty LLC); the erythromycin FDA label on DailyMed (effective August 1, 2024, Teva Pharmaceuticals USA, Inc.).
What does the amlodipine label say about erythromycin?
Amlodipine label, drug interactionsErythromycin co-administration in healthy volunteers did not significantly change amlodipine systemic exposure.
Source: FDA drug label (Norvasc), Viatris Specialty LLC, effective February 15, 2023 (SPL set 7367289c-b0b0-466a-83e2-558e2985c29f), via openFDA; the full label on DailyMed
What does the erythromycin label say about amlodipine?
Erythromycin label, warningsThese include colchicine toxicity with colchicine; rhabdomyolysis with simvastatin, lovastatin, and atorvastatin; and hypotension with calcium channel blockers metabolized by CYP3A4 (e.g., verapamil, amlodipine, diltiazem) (see PRECAUTIONS - Drug Interactions ).
Source: FDA drug label (Erythromycin), Teva Pharmaceuticals USA, Inc., effective August 1, 2024 (SPL set 75a0bd5a-d09f-483b-bfd8-f8343b149eb2), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amlodipine | Erythromycin | |
|---|---|---|
| Labeled for | High blood pressure, Angina, Heart attack and coronary artery disease | Bacterial infections, Acne |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0102 per tablet 5 mg tablet | $1.96 per tablet 250 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once