What the FDA labels say about taking them together
Amivantamab/hyaluronidase and carboplatin
Amivantamab/hyaluronidase's FDA label of June 17, 2026 names carboplatin in its warnings and precautions section; the carboplatin labels PlainMeds reads (2) do not name amivantamab/hyaluronidase. The amivantamab/hyaluronidase label: “Intravenous Amivantamab with Carboplatin and Pemetrexed Based on the pooled safety population, in 281 patients who received intravenous amivantamab in combination with carboplatin and pemetrexed, ocular toxicity …”
Check it at the source: the amivantamab/hyaluronidase FDA label on DailyMed (effective June 17, 2026); the carboplatin FDA label on DailyMed (effective January 10, 2025, Eugia US LLC).
What does the amivantamab/hyaluronidase label say about carboplatin?
Amivantamab/hyaluronidase label, warnings and precautionsIntravenous Amivantamab with Carboplatin and Pemetrexed Based on the pooled safety population [see Adverse Reactions (6.1) ], in 281 patients who received intravenous amivantamab in combination with carboplatin and pemetrexed, ocular toxicity occurred in 16%.
Source: FDA drug label (Rybrevant Faspro), Janssen Biotech, Inc., effective June 17, 2026 (SPL set 9e58b045-e352-4f62-99bf-77fae1bebc69), via openFDA; the full label on DailyMed
What does the carboplatin label say about amivantamab/hyaluronidase?
Carboplatin's label (effective January 10, 2025) and its 1 other brand-application label do not name amivantamab/hyaluronidase in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (CARBOPLATIN), Eugia US LLC, effective January 10, 2025 (SPL set f5fe9a20-47a5-45b9-ab06-c6158d9b6aca), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amivantamab/hyaluronidase | Carboplatin | |
|---|---|---|
| Labeled for | Lung cancer | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once