What the FDA labels say about taking them together
Aminophylline and theophylline
Aminophylline's FDA label of May 22, 2026 names theophylline in its contraindications section; the theophylline label PlainMeds reads does not name aminophylline. The aminophylline label: “CONTRAINDICATIONS Aminophylline is contraindicated in patients with a history of hypersensitivity to theophylline or other components in the product including ethylenediamine.”
Check it at the source: the aminophylline FDA label on DailyMed (effective May 22, 2026, Hospira, Inc.); the theophylline FDA label on DailyMed (effective March 10, 2026, Strides Pharma Science Limited).
What does the aminophylline label say about theophylline?
Aminophylline label, contraindicationsCONTRAINDICATIONS Aminophylline is contraindicated in patients with a history of hypersensitivity to theophylline or other components in the product including ethylenediamine.
Aminophylline label, drug interactionsDrug: Adenosine; Type Of Interaction: Theophylline blocks adenosine receptors.; Effect**: Higher doses of adenosine may be required to achieve desired effect.
Aminophylline label, warningsWARNINGS Concurrent Illness: Theophylline should be used with extreme caution in patients with the following clinical conditions due to the increased risk of exacerbation of the concurrent condition:
Source: FDA drug label (Aminophylline), Hospira, Inc., effective May 22, 2026 (SPL set 9a663ef3-881f-48bd-2689-3713b24545c2), via openFDA; the full label on DailyMed
What does the theophylline label say about aminophylline?
Theophylline's label (effective March 10, 2026) does not name aminophylline in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Theophylline), Strides Pharma Science Limited, effective March 10, 2026 (SPL set b7a90ccf-9c32-40cc-9008-7e55b3da4dfd), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Aminophylline | Theophylline | |
|---|---|---|
| Labeled for | Asthma | Asthma |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.330 per tablet 300 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once