Skip to main content

What the FDA labels say about taking them together

Aminophylline and nizatidine

Aminophylline's FDA label of May 22, 2026 names nizatidine in its drug interactions section; the nizatidine label PlainMeds reads does not name aminophylline. The aminophylline label: “… medroxyprogesterone methylprednisolone metronidazole metoprolol nadolol nifedipine nizatidine norfloxacin ofloxacin omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol sucralfate terbutaline …”

Check it at the source: the aminophylline FDA label on DailyMed (effective May 22, 2026, Hospira, Inc.); the nizatidine FDA label on DailyMed (effective January 2, 2025, Epic Pharma, LLC).

What does the aminophylline label say about nizatidine?

Aminophylline label, drug interactions

albuterol, systemic and inhaled amoxicillin ampicillin, with or without sulbactam atenolol azithromycin caffeine, dietary ingestion cefaclor co-trimoxazole (trimethoprim and sulfamethoxazole) diltiazem dirithromycin enflurane famotidine felodipine finasteride hydrocortisone isoflurane isoniazid isradipine influenza vaccine ketoconazole; lomefloxacin mebendazole medroxyprogesterone methylprednisolone metronidazole metoprolol nadolol nifedipine nizatidine norfloxacin ofloxacin omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol (purgative doses do not inhibit theophylline absorption) sucralfate terbutaline, systemic terfenadine tetracycline tocainide

Source: FDA drug label (Aminophylline), Hospira, Inc., effective May 22, 2026 (SPL set 9a663ef3-881f-48bd-2689-3713b24545c2), via openFDA; the full label on DailyMed

What does the nizatidine label say about aminophylline?

Nizatidine's label (effective January 2, 2025) does not name aminophylline in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Nizatidine), Epic Pharma, LLC, effective January 2, 2025 (SPL set e9957997-8b85-48a0-9bb3-b878cb223236), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

5Aminophylline generic labelers
4Nizatidine generic labelers
AminophyllineNizatidine
Labeled forAsthmaAcid reflux and ulcers
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$0.804 per capsule 150 mg capsule
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?