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What the FDA labels say about taking them together

Aminophylline and nadolol

Aminophylline's FDA label of May 22, 2026 names nadolol in its drug interactions section; the nadolol label PlainMeds reads does not name aminophylline. The aminophylline label: “… mebendazole medroxyprogesterone methylprednisolone metronidazole metoprolol nadolol nifedipine nizatidine norfloxacin ofloxacin omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol sucralfate …”

Check it at the source: the aminophylline FDA label on DailyMed (effective May 22, 2026, Hospira, Inc.); the nadolol FDA label on DailyMed (effective May 12, 2026, Amneal Pharmaceuticals NY LLC).

What does the aminophylline label say about nadolol?

Aminophylline label, drug interactions

albuterol, systemic and inhaled amoxicillin ampicillin, with or without sulbactam atenolol azithromycin caffeine, dietary ingestion cefaclor co-trimoxazole (trimethoprim and sulfamethoxazole) diltiazem dirithromycin enflurane famotidine felodipine finasteride hydrocortisone isoflurane isoniazid isradipine influenza vaccine ketoconazole; lomefloxacin mebendazole medroxyprogesterone methylprednisolone metronidazole metoprolol nadolol nifedipine nizatidine norfloxacin ofloxacin omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol (purgative doses do not inhibit theophylline absorption) sucralfate terbutaline, systemic terfenadine tetracycline tocainide

Source: FDA drug label (Aminophylline), Hospira, Inc., effective May 22, 2026 (SPL set 9a663ef3-881f-48bd-2689-3713b24545c2), via openFDA; the full label on DailyMed

What does the nadolol label say about aminophylline?

Nadolol's label (effective May 12, 2026) does not name aminophylline in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Nadolol), Amneal Pharmaceuticals NY LLC, effective May 12, 2026 (SPL set e2e24b14-0169-4028-828a-894ad3c2ba55), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

5Aminophylline generic labelers
16Nadolol generic labelers
AminophyllineNadolol
Labeled forAsthmaAngina, High blood pressure
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$0.147 per tablet 20 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?