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What the FDA labels say about taking them together

Aminophylline and lorazepam

Aminophylline's FDA label of May 22, 2026 names lorazepam in its drug interactions section, and lorazepam's label names aminophylline too. The lorazepam label: “Administration of theophylline or aminophylline may reduce the sedative effects of benzodiazepines, including lorazepam.”

Check it at the source: the aminophylline FDA label on DailyMed (effective May 22, 2026, Hospira, Inc.); the lorazepam FDA label on DailyMed (effective July 9, 2025, Bausch Health US LLC).

What does the aminophylline label say about lorazepam?

Aminophylline label, drug interactions

Lorazepam Similar to diazepam.

Source: FDA drug label (Aminophylline), Hospira, Inc., effective May 22, 2026 (SPL set 9a663ef3-881f-48bd-2689-3713b24545c2), via openFDA; the full label on DailyMed

What does the lorazepam label say about aminophylline?

Lorazepam label, drug interactions

Administration of theophylline or aminophylline may reduce the sedative effects of benzodiazepines, including lorazepam.

Source: FDA drug label (Ativan), Bausch Health US LLC, effective July 9, 2025 (SPL set 89057c93-8155-4040-acec-64e877bd2b4c), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

5Aminophylline generic labelers
36Lorazepam generic labelers
AminophyllineLorazepam
Labeled forAsthmaAnxiety
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$0.0344 per tablet 0.5 mg tablet
Shortage nowNo current entryIn shortage

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?