What the FDA labels say about taking them together
Aminophylline and ephedrine
Aminophylline's FDA label of May 22, 2026 names ephedrine in its drug interactions section; the ephedrine labels PlainMeds reads (4) do not name aminophylline. The aminophylline label: “300% increase Ephedrine Synergistic CNS effects. Increased frequency of nausea, nervousness, and insomnia.”
Check it at the source: the aminophylline FDA label on DailyMed (effective May 22, 2026, Hospira, Inc.); the ephedrine FDA label on DailyMed (effective September 16, 2024, Nexus Pharmaceuticals, LLC).
What does the aminophylline label say about ephedrine?
Aminophylline label, drug interactions300% increase Ephedrine Synergistic CNS effects. Increased frequency of nausea, nervousness, and insomnia.
Source: FDA drug label (Aminophylline), Hospira, Inc., effective May 22, 2026 (SPL set 9a663ef3-881f-48bd-2689-3713b24545c2), via openFDA; the full label on DailyMed
What does the ephedrine label say about aminophylline?
Ephedrine's label (effective September 16, 2024) and its 3 other brand-application labels do not name aminophylline in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Emerphed PFS), Nexus Pharmaceuticals, LLC, effective September 16, 2024 (SPL set 14601778-93ac-43ec-b66b-5a942317133f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Aminophylline | Ephedrine | |
|---|---|---|
| Labeled for | Asthma | Asthma |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once