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What the FDA labels say about taking them together

Aminophylline and doxapram

Doxapram's FDA label of April 9, 2024 names aminophylline in its drug interactions section; the aminophylline label PlainMeds reads does not name doxapram. The doxapram label: “There may be an interaction between doxapram and aminophylline and between doxapram and theophylline manifested by increased skeletal muscle activity, agitation, and hyperactivity.”

Check it at the source: the aminophylline FDA label on DailyMed (effective May 22, 2026, Hospira, Inc.); the doxapram FDA label on DailyMed (effective April 9, 2024, Hikma Pharmaceuticals USA Inc.).

What does the aminophylline label say about doxapram?

Aminophylline's label (effective May 22, 2026) does not name doxapram in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Aminophylline), Hospira, Inc., effective May 22, 2026 (SPL set 9a663ef3-881f-48bd-2689-3713b24545c2), via openFDA; the full label on DailyMed

What does the doxapram label say about aminophylline?

Doxapram label, drug interactions

There may be an interaction between doxapram and aminophylline and between doxapram and theophylline manifested by increased skeletal muscle activity, agitation, and hyperactivity.

Source: FDA drug label (Dopram), Hikma Pharmaceuticals USA Inc., effective April 9, 2024 (SPL set b8eb330a-a75b-46cb-b694-5be9327ed2eb), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

5Aminophylline generic labelers
0Doxapram generic labelers
AminophyllineDoxapram
Labeled forAsthman/a
Boxed warningNoNo
Pharmacy cost (NADAC)n/an/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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