What the FDA labels say about taking them together
Amantadine and rimantadine
Rimantadine's FDA label of December 31, 2023 names amantadine in its contraindications section; the amantadine labels PlainMeds reads (2) do not name rimantadine. The rimantadine label: “CONTRAINDICATIONS Rimantadine hydrochloride tablet is contraindicated in patients with known hypersensitivity to drugs of the adamantane class, including rimantadine and amantadine.”
Check it at the source: the amantadine FDA label on DailyMed (effective January 30, 2026, Strides Pharma Inc.); the rimantadine FDA label on DailyMed (effective December 31, 2023, Amneal Pharmaceuticals of New York LLC).
What does the amantadine label say about rimantadine?
Amantadine's label (effective January 30, 2026) and its 1 other brand-application label do not name rimantadine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Amantadine Hydrochloride), Strides Pharma Inc., effective January 30, 2026 (SPL set e4d8f36f-d668-4728-8dca-b1c22bd9aedb), via openFDA; the full label on DailyMed
What does the rimantadine label say about amantadine?
Rimantadine label, contraindicationsCONTRAINDICATIONS Rimantadine hydrochloride tablet is contraindicated in patients with known hypersensitivity to drugs of the adamantane class, including rimantadine and amantadine.
Source: FDA drug label (Rimantadine Hydrochloride), ANDA076132 (Impax Labs), as published by Amneal Pharmaceuticals of New York LLC, effective December 31, 2023 (SPL set 49f7d69a-820b-4c75-a31d-b2104c019c12), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amantadine | Rimantadine | |
|---|---|---|
| Labeled for | Influenza, Parkinson's disease | Influenza |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.143 per capsule 100 mg capsule | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once