What the FDA labels say about taking them together
Amantadine and quinine
Amantadine's FDA label of January 30, 2026 names quinine in its drug interactions section; the quinine label PlainMeds reads does not name amantadine. The amantadine label: “Coadministration of quinine or quinidine with amantadine was shown to reduce the renal clearance of amantadine by about 30%.”
Check it at the source: the amantadine FDA label on DailyMed (effective January 30, 2026, Strides Pharma Inc.); the quinine FDA label on DailyMed (effective November 9, 2023).
What does the amantadine label say about quinine?
Amantadine label, drug interactionsCoadministration of quinine or quinidine with amantadine was shown to reduce the renal clearance of amantadine by about 30%.
Source: FDA drug label (Amantadine Hydrochloride), Strides Pharma Inc., effective January 30, 2026 (SPL set e4d8f36f-d668-4728-8dca-b1c22bd9aedb), via openFDA; the full label on DailyMed
What does the quinine label say about amantadine?
Quinine's label (effective November 9, 2023) does not name amantadine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Chininum sulphuricum), Boiron, effective November 9, 2023 (SPL set 33885950-2a55-11e7-8288-424c58303031), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amantadine | Quinine | |
|---|---|---|
| Labeled for | Influenza, Parkinson's disease | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.143 per capsule 100 mg capsule | $0.698 per capsule 324 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once