What the FDA labels say about taking them together
Amantadine and quinidine
Amantadine's FDA label of January 30, 2026 names quinidine in its drug interactions section; the quinidine label PlainMeds reads does not name amantadine. The amantadine label: “Coadministration of quinine or quinidine with amantadine was shown to reduce the renal clearance of amantadine by about 30%.”
Check it at the source: the amantadine FDA label on DailyMed (effective January 30, 2026, Strides Pharma Inc.); the quinidine FDA label on DailyMed (effective February 1, 2018, Sun Pharmaceutical Industries, Inc.).
What does the amantadine label say about quinidine?
Amantadine label, drug interactionsCoadministration of quinine or quinidine with amantadine was shown to reduce the renal clearance of amantadine by about 30%.
Source: FDA drug label (Amantadine Hydrochloride), Strides Pharma Inc., effective January 30, 2026 (SPL set e4d8f36f-d668-4728-8dca-b1c22bd9aedb), via openFDA; the full label on DailyMed
What does the quinidine label say about amantadine?
Quinidine's label (effective February 1, 2018) does not name amantadine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Quinidine Gluconate), Sun Pharmaceutical Industries, Inc., effective February 1, 2018 (SPL set 5023f053-fcc4-4c2c-aa59-9ec198ad185e), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amantadine | Quinidine | |
|---|---|---|
| Labeled for | Influenza, Parkinson's disease | Atrial fibrillation |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.143 per capsule 100 mg capsule | $4.92 per tablet 324 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once