What the FDA labels say about taking them together
Alosetron and teriflunomide
Teriflunomide's FDA label of February 20, 2026 names alosetron in its drug interactions section; the alosetron label PlainMeds reads does not name teriflunomide. The teriflunomide label: “In patients taking AUBAGIO, exposure of drugs metabolized by CYP1A2 may be reduced.”
Check it at the source: the alosetron FDA label on DailyMed (effective March 23, 2026, Legacy Pharma USA Inc.); the teriflunomide FDA label on DailyMed (effective February 20, 2026, Genzyme Corporation).
What does the alosetron label say about teriflunomide?
Alosetron's label (effective March 23, 2026) does not name teriflunomide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (LOTRONEX), Legacy Pharma USA Inc., effective March 23, 2026 (SPL set c216e967-436f-475a-8e6a-2ad11adc63af), via openFDA; the full label on DailyMed
What does the teriflunomide label say about alosetron?
Teriflunomide label, drug interactionsIn patients taking AUBAGIO, exposure of drugs metabolized by CYP1A2 (e.g., alosetron, duloxetine, theophylline, tizanidine) may be reduced.
Source: FDA drug label (Aubagio), NDA202992 (Sanofi Aventis Us), as published by Genzyme Corporation, effective February 20, 2026 (SPL set 4650d12c-b9c8-4525-b07f-a2d773eca155), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Alosetron | Teriflunomide | |
|---|---|---|
| Labeled for | n/a | Multiple sclerosis |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $2.02 per tablet 0.5 mg tablet | $0.233 per tablet 14 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once