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What the FDA labels say about taking them together

Alosetron and deferasirox

Deferasirox's FDA label of January 28, 2026 names alosetron in its drug interactions section; the alosetron label PlainMeds reads does not name deferasirox. The deferasirox label: “Metabolized by CYP1A2 Deferasirox inhibits CYP1A2 resulting in an increase in CYP1A2 substrate concentration when these drugs are coadministered.”

Check it at the source: the alosetron FDA label on DailyMed (effective March 23, 2026, Legacy Pharma USA Inc.); the deferasirox FDA label on DailyMed (effective January 28, 2026, Novartis Pharmaceuticals Corporation).

What does the alosetron label say about deferasirox?

Alosetron's label (effective March 23, 2026) does not name deferasirox in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (LOTRONEX), Legacy Pharma USA Inc., effective March 23, 2026 (SPL set c216e967-436f-475a-8e6a-2ad11adc63af), via openFDA; the full label on DailyMed

What does the deferasirox label say about alosetron?

Deferasirox label, drug interactions

Metabolized by CYP1A2 Deferasirox inhibits CYP1A2 resulting in an increase in CYP1A2 substrate (e.g., alosetron, caffeine, duloxetine, melatonin, ramelteon, tacrine, theophylline, tizanidine) concentration when these drugs are coadministered.

Source: FDA drug label (Exjade), Novartis Pharmaceuticals Corporation, effective January 28, 2026 (SPL set 3495a70c-870c-4968-940e-8baea152cf85), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

6Alosetron generic labelers
20Deferasirox generic labelers
AlosetronDeferasirox
Labeled forn/an/a
Boxed warningYesYes
Pharmacy cost (NADAC)$2.02 per tablet 0.5 mg tablet$1.25 per tablet 360 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?