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What the FDA labels say about taking them together

Almotriptan and citalopram

Almotriptan's FDA label of December 31, 2025 names citalopram in its warnings and precautions section; the citalopram labels PlainMeds reads (2) do not name almotriptan. The almotriptan label: “If concomitant treatment with almotriptan tablets and an SSRI or SNRI is clinically warranted, careful observation of the patient is advised, particularly during treatment initiation and dose increases.”

Check it at the source: the almotriptan FDA label on DailyMed (effective December 31, 2025, Ajanta Pharma USA Inc.); the citalopram FDA label on DailyMed (effective October 9, 2023, Allergan, Inc.).

What does the almotriptan label say about citalopram?

Almotriptan label, warnings and precautions

If concomitant treatment with almotriptan tablets and an SSRI (e.g., fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, escitalopram) or SNRI (e.g., venlafaxine, duloxetine) is clinically warranted, careful observation of the patient is advised, particularly during treatment initiation and dose increases.

Source: FDA drug label (almotriptan), Ajanta Pharma USA Inc., effective December 31, 2025 (SPL set 6fa380c4-c885-4743-85bf-88819ae68645), via openFDA; the full label on DailyMed

What does the citalopram label say about almotriptan?

Citalopram's label (effective October 9, 2023) and its 1 other brand-application label do not name almotriptan in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Celexa), NDA020822 (Abbvie), as published by Allergan, Inc., effective October 9, 2023 (SPL set 4259d9b1-de34-43a4-85a8-41dd214e9177), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

3Almotriptan generic labelers
35Citalopram generic labelers
AlmotriptanCitalopram
Labeled forMigraine, PainDepression
Boxed warningNoYes
Pharmacy cost (NADAC)$16.86 per tablet 12.5 mg tablet$0.026 per tablet 10 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?