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What the FDA labels say about taking them together

Alitretinoin and itraconazole

Itraconazole's FDA label of July 13, 2026 names alitretinoin in its drug interactions section; the alitretinoin label PlainMeds reads does not name itraconazole. The itraconazole label: “Alitretinoin (oral) Cabergoline Cannabinoids Cinacalcet Ivacaftor Monitor for adverse reactions.”

Check it at the source: the alitretinoin FDA label on DailyMed (effective November 25, 2025, Advanz Pharma (US) Corp.); the itraconazole FDA label on DailyMed (effective July 13, 2026, Janssen Pharmaceuticals, Inc.).

What does the alitretinoin label say about itraconazole?

Alitretinoin's label (effective November 25, 2025) does not name itraconazole in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (PANRETIN), Advanz Pharma (US) Corp., effective November 25, 2025 (SPL set 49c16717-7d86-4257-80c9-baa1417e5555), via openFDA; the full label on DailyMed

What does the itraconazole label say about alitretinoin?

Itraconazole label, drug interactions

Alitretinoin (oral) Cabergoline Cannabinoids Cinacalcet Galantamine Ivacaftor Monitor for adverse reactions.

Source: FDA drug label (Tolsura, NDA208901), Mayne Pharma Commercial LLC, effective April 23, 2025 (SPL set 306352d1-9d5a-49ad-b72d-893b99546861), via openFDA

Source: FDA drug label (SPORANOX), Janssen Pharmaceuticals, Inc., effective July 13, 2026 (SPL set a4d555fa-787c-40fb-bb7d-b0d4f7318fd0), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Alitretinoin generic labelers
11Itraconazole generic labelers
AlitretinoinItraconazole
Labeled forn/aFungal infections
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$0.910 per capsule 100 mg capsule
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?