What the FDA labels say about taking them together
Alfuzosin and atazanavir
Atazanavir's FDA label of August 6, 2025 names alfuzosin in its contraindications section; the alfuzosin label PlainMeds reads does not name atazanavir. The atazanavir label: “Coadministration of REYATAZ with alfuzosin is contraindicated due to risk for hypotension.”
Check it at the source: the alfuzosin FDA label on DailyMed (effective December 5, 2024, Advanz Pharma (US) Corp.); the atazanavir FDA label on DailyMed (effective August 6, 2025, Aurobindo Pharma Limited).
What does the alfuzosin label say about atazanavir?
Alfuzosin's label (effective December 5, 2024) does not name atazanavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Uroxatral), Advanz Pharma (US) Corp., effective December 5, 2024 (SPL set 9fc7f119-f36b-44cf-945d-940160f3afe3), via openFDA; the full label on DailyMed
What does the atazanavir label say about alfuzosin?
Atazanavir label, contraindicationsDrug Class: Alpha 1-adrenoreceptor antagonist; Drugs within class that are contraindicated with atazanavir capsules: Alfuzosin
Atazanavir label, drug interactionsConcomitant Drug Class/Specific Drugs: Alpha 1-Adrenoreceptor Antagonist: alfuzosin; Effect on Concentration of Atazanavir or Concomitant Drug: ↑ alfuzosin; Clinical Comment: Coadministration of atazanavir with alfuzosin is contraindicated due to risk for hypotension [see ].
Source: FDA drug label (Reyataz, NDA021567), E.R. Squibb & Sons, L.L.C., effective December 5, 2024 (SPL set 165cff62-b284-4a27-a65d-9ec8a5bfcdd8), via openFDA
Source: FDA drug label (Atazanavir Sulfate), Aurobindo Pharma Limited, effective August 6, 2025 (SPL set 7fbea274-d6b5-4faa-bbf0-05fefab42114), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Alfuzosin | Atazanavir | |
|---|---|---|
| Labeled for | Enlarged prostate (BPH) | HIV |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.105 per tablet 10 mg tablet | $2.23 per capsule 300 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once