What the FDA labels say about taking them together
Adefovir dipivoxil and tacrolimus
Adefovir dipivoxil's FDA label of July 22, 2025 names tacrolimus in its warnings and precautions section; the tacrolimus labels PlainMeds reads (4) do not name adefovir dipivoxil. The adefovir dipivoxil label: “… and patients taking concomitant nephrotoxic agents such as cyclosporine, tacrolimus, aminoglycosides, vancomycin and non-steroidal anti-inflammatory drugs.”
Check it at the source: the adefovir dipivoxil FDA label on DailyMed (effective July 22, 2025, Apotex Corp.); the tacrolimus FDA label on DailyMed (effective July 17, 2026, Stellon Biotech Inc.).
What does the adefovir dipivoxil label say about tacrolimus?
Adefovir dipivoxil label, warnings and precautionsHowever, this is of special importance in patients at risk of or having underlying renal dysfunction and patients taking concomitant nephrotoxic agents such as cyclosporine, tacrolimus, aminoglycosides, vancomycin and non-steroidal anti-inflammatory drugs [See Adverse Reactions (6.2) and Clinical Pharmacology (12.3) ].
Source: FDA drug label (Adefovir dipivoxil), Apotex Corp., effective July 22, 2025 (SPL set 08e07fae-3191-b6a3-c894-d3a8cc53923f), via openFDA; the full label on DailyMed
What does the tacrolimus label say about adefovir dipivoxil?
Tacrolimus's label (effective July 17, 2026) and its 3 other brand-application labels do not name adefovir dipivoxil in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Tacrolimus), Stellon Biotech Inc., effective July 17, 2026 (SPL set 6b89e8a4-9f11-42e3-8e79-fe617e7c461f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Adefovir dipivoxil | Tacrolimus | |
|---|---|---|
| Labeled for | Hepatitis B | Organ transplant rejection, Eczema (atopic dermatitis) |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $21.73 per tablet 10 mg tablet | $0.970 per gram 0.1% ointment |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once