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What the FDA labels say about taking them together

Adalimumab-fkjp and mercaptopurine

Adalimumab-fkjp's FDA label of January 12, 2026 names mercaptopurine in its warnings and precautions section; the mercaptopurine labels PlainMeds reads (2) do not name adalimumab-fkjp. The adalimumab-fkjp label: “The potential risk with the combination of azathioprine or 6- mercaptopurine and Adalimumab-fkjp should be carefully considered.”

Check it at the source: the adalimumab-fkjp FDA label on DailyMed (effective January 12, 2026, Biocon Biologics Inc); the mercaptopurine FDA label on DailyMed (effective July 20, 2026, Nova Laboratories, Ltd).

What does the adalimumab-fkjp label say about mercaptopurine?

Adalimumab-fkjp label, warnings and precautions

The potential risk with the combination of azathioprine or 6- mercaptopurine and Adalimumab-fkjp should be carefully considered.

Source: FDA drug label (Adalimumab), BLA761154 (Mylan Pharms Inc), as published by Biocon Biologics Inc, effective January 12, 2026 (SPL set 5cde907d-6747-0e62-db25-1718ee717fe7), via openFDA; the full label on DailyMed

What does the mercaptopurine label say about adalimumab-fkjp?

Mercaptopurine's label (effective July 20, 2026) and its 1 other brand-application label do not name adalimumab-fkjp in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (MERCAPTOPURINE), Nova Laboratories, Ltd, effective July 20, 2026 (SPL set 9c6fc66b-522f-499d-961a-cde6ca0ec2e5), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Adalimumab-fkjp generic labelers
2Mercaptopurine generic labelers
Adalimumab-fkjpMercaptopurine
Labeled forRheumatoid arthritis, Crohn's disease and ulcerative colitis, PsoriasisLeukemia, lymphoma and myeloma
Boxed warningYesNo
Pharmacy cost (NADAC)n/a$1.07 per tablet 50 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?