What the FDA labels say about taking them together
Acyclovir and mycophenolic acid
Mycophenolic acid's FDA label of July 29, 2026 names acyclovir in its drug interactions section; the acyclovir labels PlainMeds reads (4) do not name mycophenolic acid. The mycophenolic acid label: “Acyclovir (Valacyclovir), Ganciclovir (Valganciclovir), and Other Drugs That Undergo Renal Tubular Secretion The coadministration of MMF and acyclovir or ganciclovir may increase plasma concentrations of mycophenolic …”
Check it at the source: the acyclovir FDA label on DailyMed (effective July 24, 2026, Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.); the mycophenolic acid FDA label on DailyMed (effective July 29, 2026, Novartis Pharmaceuticals Corporation).
What does the acyclovir label say about mycophenolic acid?
Acyclovir's label (effective July 24, 2026) and its 3 other brand-application labels do not name mycophenolic acid in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ACYCLOVIR), Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effective July 24, 2026 (SPL set 0de2f5c7-9e75-4bdf-9c28-e026cc6694b4), via openFDA; the full label on DailyMed
What does the mycophenolic acid label say about acyclovir?
Mycophenolic acid label, drug interactionsAcyclovir (Valacyclovir), Ganciclovir (Valganciclovir), and Other Drugs That Undergo Renal Tubular Secretion The coadministration of MMF and acyclovir or ganciclovir may increase plasma concentrations of mycophenolic acid glucuronide (MPAG) and acyclovir/valacyclovir/ganciclovir/valganciclovir as their coexistence competes for tubular secretion.
Source: FDA drug label (Myfortic), Novartis Pharmaceuticals Corporation, effective July 29, 2026 (SPL set eed26501-890d-4ff6-88e7-6dbea4726e53), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Acyclovir | Mycophenolic acid | |
|---|---|---|
| Labeled for | Herpes and shingles | Organ transplant rejection |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.0962 per tablet 400 mg tablet | $0.0996 per tablet 180 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once