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What the FDA labels say about taking them together

Acitretin and vitamin a

Acitretin's FDA label of August 5, 2026 names vitamin a in its drug interactions section; the vitamin a label PlainMeds reads does not name acitretin. The acitretin label: “Vitamin A and Oral Retinoids: Concomitant administration of vitamin A and/or other oral retinoids with acitretin must be avoided because of the risk of hypervitaminosis A.”

Check it at the source: the acitretin FDA label on DailyMed (effective August 5, 2026, Sigmapharm Laboratories, LLC); the vitamin a FDA label on DailyMed (effective March 3, 2026, Rising Pharma Holdings, Inc.).

What does the acitretin label say about vitamin a?

Acitretin label, drug interactions

Vitamin A and Oral Retinoids: Concomitant administration of vitamin A and/or other oral retinoids with acitretin must be avoided because of the risk of hypervitaminosis A.

Source: FDA drug label (ACITRETIN), Sigmapharm Laboratories, LLC, effective August 5, 2026 (SPL set a6546625-acb8-460e-b34e-f795bfb3680a), via openFDA; the full label on DailyMed

What does the vitamin a label say about acitretin?

Vitamin a's label (effective March 3, 2026) does not name acitretin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (AQUASOL A Parenteral), Rising Pharma Holdings, Inc., effective March 3, 2026 (SPL set 1abd66eb-6ac8-4a9e-a609-251e46ea1a27), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

8Acitretin generic labelers
0Vitamin a generic labelers
AcitretinVitamin a
Labeled forPsoriasisn/a
Boxed warningYesNo
Pharmacy cost (NADAC)$2.59 per capsule 10 mg capsulen/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?